<![CDATA[Faster NGS Duplicate Marking]]>https://medium.com/grail-eng/faster-ngs-duplicate-marking-d7a1fd287f46
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Picard¹ and Sambamba 的算法类似
SAMTools (rmdup)

]]>http://an.forum.genostack.com/topic/637/faster-ngs-duplicate-markingRSS for NodeSat, 13 Jun 2026 09:22:21 GMTMon, 09 May 2022 08:52:37 GMT60<![CDATA[Reply to Faster NGS Duplicate Marking on Mon, 09 May 2022 08:53:32 GMT]]>https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-016-1097-3#:~:text=PCR duplicates are sequence reads,duplicates appear proportionately more often
这个文章说去重对后面的variant call 结果影响不大 但是这样能明显减少分析的数据量

]]>http://an.forum.genostack.com/post/1461http://an.forum.genostack.com/post/1461Mon, 09 May 2022 08:53:32 GMT