免疫组学基础
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白血细胞
白细胞由粒细胞、树突状细胞、巨噬细胞和淋巴细胞组成，在人体防御中发挥重要作用，可消除病毒和恶性细胞等入侵病原体。淋巴细胞的主要类型是 T 细胞和 B 细胞，它们分别在表面表达识别抗原的受体，即 T 细胞受体 (TCR) 和 B 细胞受体 (BCR)。它们被激活以启动免疫反应，以响应其受体与肿瘤和病毒等抗原的特定结合。通过基因重排和体细胞超突变的机制，产生了种类繁多的 TCR 和 BCR，以对各种抗原作出反应。TCR 的种类估计达到 1018，BCR 的种类估计达到 1014。
A type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. White blood cells are part of the body’s immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosinophils, and basophils), monocytes, and lymphocytes (T cells and B cells). Checking the number of white blood cells in the blood is usually part of a complete blood cell (CBC) test. It may be used to look for conditions such as infection, inflammation, allergies, and leukemia. Also called leukocyte and WBC.
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/white-blood-cell
https://www.repertoire.co.jp/en/research/technology/repertoire/
TCR和BCR受体
T cell receptor (TCR) and B cell receptor (BCR)TCR/BCR repertoire
T细胞组库基因结构
T Cell Receptor (TCR) Gene Structure抗体
https://www.abcam.com/en-us/technical-resources/guides/antibody-basics/antibody-basics
抗体的类型
表位和互补位
