注释数据库
-
GENCODE or ENCODE
GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project.
The Encyclopedia of DNA Elements (ENCODE) is a public research project which aims to identify functional elements in the human genome.
The most recent release of the Human geneset annotations is Gencode 32, with a freeze date of September 2019. This release utilises the latest GRCh38 human reference genome assembly.

-
人的参考基因组有两个主要的来源,UCSC hg19 和 GRCh37 这两个的染色体编号不同 所以建议用 GRCh37的 这样注释也都来自 gencode
There are a few minor differences between GRCh37 and hg19. The contig sequences are the same but the names are different, i.e. "1" may need to be converted to "chr1". In addition UCSC hg19 is currenly using the old mitochondrial sequence but NCBI and Ensembl have transitioned to NC_012920. -
https://www.well.ox.ac.uk/ogc/guide-reference-genome-selection/
A guide to reference genome selection
