大队列研究项目汇总
-
一，Centers for Common Disease Genomics
https://www.genome.gov/Funded-Programs-Projects/NHGRI-Genome-Sequencing-Program/Centers-for-Common-Disease-Genomics
The CCDGs study 9个常见疾病 试图找出这些疾病和遗传的关系
cardiovascular diseases (early-onset cardiovascular disease, atrial fibrillation, hemorrhagic stroke),
neuropsychiatric diseases (autism, Alzheimer's disease, epilepsy), immune-mediated diseases (irritable bowel disorder, asthma, Type-1 diabetes).https://bravo.sph.umich.edu/freeze8/hg38/
https://www.nature.com/articles/s41586-021-03205-y -
NHLBI Trans-Omics for Precision Medicine
The Trans-Omics for Precision Medicine (TOPMed) program, sponsored by the National Institutes of Health (NIH) National Heart, Lung and Blood Institute (NHLBI), is part of a broader Precision Medicine Initiative, which aims to provide disease treatments tailored to an individual’s unique genes and environment. TOPMed contributes to this Initiative through the integration of whole-genome sequencing (WGS) and other omics (e.g., metabolic profiles, epigenomics, protein and RNA expression patterns) data with molecular, behavioral, imaging, environmental, and clinical data. -
https://www.internationalgenome.org/
IGSR: The International Genome Sample Resource -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335588/
The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases -
https://www.nature.com/articles/s41597-019-0205-4
The Personal Genome Project UK (PGP-UK)
www.personalgenomes.org.uk -
-